Johns Hopkins ABX Guide
Clostridium tetani (Tetanus)
Clostridium tetani (Tetanus) is a topic covered in the Johns Hopkins ABX Guide.
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MICROBIOLOGY
- Clostridium tetani is a Gram-positive bacillus, obligate anaerobe.
- If culture enters the endospore stage, may have classic tennis racquet morphology [Fig 1].
- Spore widespread in soil and animal feces.
- Rod-shaped appearance on gram stain often likened to drumsticks or tennis rackets.
- Toxin, tetanospasmin, causes tetanus: unopposed muscle spasm, contraction due to interference of toxin with neurotransmitters (including GABA and glycine).
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MICROBIOLOGY
- Clostridium tetani is a Gram-positive bacillus, obligate anaerobe.
- If culture enters the endospore stage, may have classic tennis racquet morphology [Fig 1].
- Spore widespread in soil and animal feces.
- Rod-shaped appearance on gram stain often likened to drumsticks or tennis rackets.
- Toxin, tetanospasmin, causes tetanus: unopposed muscle spasm, contraction due to interference of toxin with neurotransmitters (including GABA and glycine).
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Last updated: September 27, 2019
Citation
Auwaerter, Paul. "Clostridium Tetani (Tetanus)." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540136/all/Clostridium_tetani__Tetanus_.
Auwaerter P. Clostridium tetani (Tetanus). Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540136/all/Clostridium_tetani__Tetanus_. Accessed July 7, 2022.
Auwaerter, P. (2019). Clostridium tetani (Tetanus). In Johns Hopkins ABX Guide. The Johns Hopkins University. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540136/all/Clostridium_tetani__Tetanus_
Auwaerter P. Clostridium Tetani (Tetanus) [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2022 July 07]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540136/all/Clostridium_tetani__Tetanus_.
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