Johns Hopkins ABX Guide
Cefpodoxime proxetil
Cefpodoxime proxetil is a topic covered in the Johns Hopkins ABX Guide.
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INDICATIONS
FDA
FDA
- Upper respiratory tract infections including acute otitis media, pharyngitis, tonsillitis, acute exacerbation of chronic bronchitis (AECB), and acute maxillary sinusitis
- Acute uncomplicated urethral and cervical gonorrhea and ano-rectal gonorrhea (females) caused by N. gonorrhoeae (no longer recommended by CDC) [3]
- Uncomplicated skin and skin-structure infections S. aureus (MSSA) or S. pyogenes.
- Uncomplicated urinary tract infections caused by E. coli, K. pneumoniae, P. mirabilis, or S. saprophyticus.
- Community-acquired pneumonia (CAP) caused by S. pneumoniae or H. influenzae
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Prophylaxis in neutropenic fever in patients who are intolerant of fluoroquinolones
- Oral alternative therapy for pyelonephritis without bacteremia in patients who are resistant to fluoroquinolones or trimethoprim/sulfamethoxazole.
- IDSA recommends that if oral β-lactams are to be empirically used, initial intravenous dose of a long-acting parenteral antimicrobial such as 1 g of ceftriaxone or a consolidated 24-h dose of an aminoglycoside be administered first[1].
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INDICATIONS
FDA
FDA
- Upper respiratory tract infections including acute otitis media, pharyngitis, tonsillitis, acute exacerbation of chronic bronchitis (AECB), and acute maxillary sinusitis
- Acute uncomplicated urethral and cervical gonorrhea and ano-rectal gonorrhea (females) caused by N. gonorrhoeae (no longer recommended by CDC) [3]
- Uncomplicated skin and skin-structure infections S. aureus (MSSA) or S. pyogenes.
- Uncomplicated urinary tract infections caused by E. coli, K. pneumoniae, P. mirabilis, or S. saprophyticus.
- Community-acquired pneumonia (CAP) caused by S. pneumoniae or H. influenzae
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Prophylaxis in neutropenic fever in patients who are intolerant of fluoroquinolones
- Oral alternative therapy for pyelonephritis without bacteremia in patients who are resistant to fluoroquinolones or trimethoprim/sulfamethoxazole.
- IDSA recommends that if oral β-lactams are to be empirically used, initial intravenous dose of a long-acting parenteral antimicrobial such as 1 g of ceftriaxone or a consolidated 24-h dose of an aminoglycoside be administered first[1].
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Last updated: March 4, 2018
Citation
Avdic, Edina, and Paul A Pham. "Cefpodoxime Proxetil." Johns Hopkins ABX Guide, The Johns Hopkins University, 2018. Johns Hopkins Guides, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540098/all/Cefpodoxime_proxetil.
Avdic E, Pham PA. Cefpodoxime proxetil. Johns Hopkins ABX Guide. The Johns Hopkins University; 2018. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540098/all/Cefpodoxime_proxetil. Accessed February 9, 2023.
Avdic, E., & Pham, P. A. (2018). Cefpodoxime proxetil. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540098/all/Cefpodoxime_proxetil
Avdic E, Pham PA. Cefpodoxime Proxetil [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2018. [cited 2023 February 09]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540098/all/Cefpodoxime_proxetil.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Cefpodoxime proxetil
ID - 540098
A1 - Avdic,Edina,Pharm.D., BCPS
AU - Pham,Paul,Pharm.D.
Y1 - 2018/03/04/
BT - Johns Hopkins ABX Guide
UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540098/all/Cefpodoxime_proxetil
PB - The Johns Hopkins University
DB - Johns Hopkins Guides
DP - Unbound Medicine
ER -
