Molnupiravir
Kathryn Dzintars, Pharm.D., BCPS
Molnupiravir is a topic covered in the
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INDICATIONS
The FDA issued an Emergency Use Authorization (EUA) for the emergency use of molnupiravir for the treatment of mild-to-moderate COVID-19 in adults at high risk for progressing to severe COVID-19 disease, including hospitalization and death.
- Risk for progression includes age > 60, diabetes, obesity (BMI ≥ 30), chronic kidney disease, serious heart conditions, chronic obstructive pulmonary disease, or active cancer.
- Authorized for treatment within the first 5d of symptomatic COVID-19 illness.
- In February 2023, the FDA updated the EUA by removing the need for a positive COVID-19 viral test to prescribe the medication
Molnupiravir is NOT authorized for:
- Patients < 18 years of age
- Patients requiring hospitalization for the management of COVID-19 disease (benefit has not been observed in patients beginning treatment after hospitalization)
- Use longer than 5 consecutive days
- Pre-exposure or post-exposure prophylaxis for the prevention of COVID-19 disease
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INDICATIONS
The FDA issued an Emergency Use Authorization (EUA) for the emergency use of molnupiravir for the treatment of mild-to-moderate COVID-19 in adults at high risk for progressing to severe COVID-19 disease, including hospitalization and death.
- Risk for progression includes age > 60, diabetes, obesity (BMI ≥ 30), chronic kidney disease, serious heart conditions, chronic obstructive pulmonary disease, or active cancer.
- Authorized for treatment within the first 5d of symptomatic COVID-19 illness.
- In February 2023, the FDA updated the EUA by removing the need for a positive COVID-19 viral test to prescribe the medication
Molnupiravir is NOT authorized for:
- Patients < 18 years of age
- Patients requiring hospitalization for the management of COVID-19 disease (benefit has not been observed in patients beginning treatment after hospitalization)
- Use longer than 5 consecutive days
- Pre-exposure or post-exposure prophylaxis for the prevention of COVID-19 disease
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