Primaquine

Janessa Smith, Pharm.D. BCPS, Paul A. Pham, Pharm.D.
Primaquine is a topic covered in the Johns Hopkins HIV Guide.

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INDICATIONS

FDA

  • Malaria treatment or prevention of relapses caused by Plasmodium vivax. Also effective against gametocytes of P. falciparum.

NON-FDA APPROVED USES

  • Treatment of Pneumocystis jirovecii pneumonia (PCP) (in combination with clindamycin).
  • Prevention and treatment of uncomplicated P. ovale malaria
  • Presumptive antirelapse therapy for P. ovale malaria

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INDICATIONS

FDA

  • Malaria treatment or prevention of relapses caused by Plasmodium vivax. Also effective against gametocytes of P. falciparum.

NON-FDA APPROVED USES

  • Treatment of Pneumocystis jirovecii pneumonia (PCP) (in combination with clindamycin).
  • Prevention and treatment of uncomplicated P. ovale malaria
  • Presumptive antirelapse therapy for P. ovale malaria

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