Post-exposure prophylaxis

Christopher J. Hoffmann, M.D., M.P.H., Michael Melia, M.D.

DEFINITION

Exposure to HIV is a medical emergency. post-exposure prophylaxis (PEP) should be initiated within 2 hours and no later than 72 hours after exposure.
Often classified as occupational (oPEP; e.g., needlestick), non-occupational (nPEP; sexual exposure or injection drug use)

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