Metronidazole

Metronidazole is a topic covered in the Johns Hopkins HIV Guide.

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INDICATIONS

FDA

  • Anaerobic infections: Intra-abdominal infections; skin and skin structure infections and bone and joint infections
  • Bacterial septicemia; endocarditis (caused by Bacteroides spp.).
  • Gynecologic infections (endometritis, endomyometritis, tubo-ovarian abscess, and postsurgical vaginal cuff infection).
  • Lower respiratory tract infections (in combination with another agent with activity against microaerophilic Streptococcus).
  • Adjunct treatment for gastritis and duodenal ulcer associated with Helicobacter pylori.
  • CNS infections (meningitis and brain abscess).
  • Treatment of acute intestinal amebiasis and amebic liver abscess.
  • Treatment of symptomatic and asymptomatic trichomoniasis.
  • Bacterial vaginosis (vaginal gel)
  • Rosacea (topical gel).

NON-FDA APPROVED USES

  • Colitis, antibiotic-associated (treatment).
  • Periodontal disease
  • Elective colorectal surgery prophylaxis (classified as contaminated or potentially contaminated).
  • Treatment of giardiasis and dracunculiasis

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