Cardiomyopathy, Myocarditis, Pericarditis, and Endocarditis

Christopher J. Hoffmann, M.D., M.P.H.

PATHOGENS

HIV: myocarditis (possibly) and increased inflammation leading to myocardial fibrosis and steatosis (diastolic and systolic heart failure) and atherosclerosis
Increasing diastolic dysfunction (symptomatic and asymptomatic), attributed to older age and chronic HTN
Cytomegalovirus: myocarditis
Cryptococcus neoformans: myocarditis
Epstein-Barr virus: myocarditis (rare)
Herpes simplex virus: myocarditis
HHV-8: associated with pulmonary hypertension. KS-related pericardial effusion, cardiac tumors
Mycobacterium spp.: pericarditis, myocarditis [TB>>MAI]
Staphylococcus spp.: endocarditis, purulent pericarditis
Streptococcus pneumoniae: purulent pericarditis
Toxoplasma gondii: myocarditis
Enterovirus (coxsackie, echovirus): myocarditis, pericarditis
Nocardia spp.: pericarditis
Histoplasma capsulatum: pericarditis
Cryptococcus neoformans: pericarditis
HIV: myocarditis

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