Comment: Factors associated with greater CGM use was age > 25 years and more frequent self reported pre study blood glucose meter measurements per day. More frequent CGM use associated with greater reduction in HbA1c after 6 months, in all age groups.
Comment: Evaluated long term effects of CGM in intensively-treated adults with type 1 diabetes. CGM use and benefit sustained for 12 months in this population.
Comment: Study examined CGM benefits for patients with type 1 diabetes who have already achieved HbA1c levels < 7.0 %. Most outcomes, including those combining A1c and hypoglycemia, better with CGM group.
Comment: Landmark study evaluating the value of CGM in management of type 1 diabetes mellitus. Results suggested CGM can be associated with lower HbA1c levels in adults with T1DM.
Comment: Study revealed patients using CGM spent less time in hypoglycemic and hyperglycemic range, more time at target glucose range, and had less nocturnal hypoglycemia; no difference in A1C levels.
Comment: Real-time recognition of both the absolute magnitude of glycemia and trend patterns provides enormous, useful information to patient.
Comment: Study revealed fewer hypoglycemic events per day (1.4 + 1.1 vs. 1.7 + 1.2; p value .30) as well as a shorter duration of the event (49.4 + 40.8 minutes per event vs. 81.0 + 61.1 minutes per event; p value .009) in a group of patients using the CGM as compared to a control group using SMBG.
Comment: Physiological lag between capillary blood glucose data and interstitial fluid sensor data can be as much as 4-10 minutes, depending on rate of glucose change.
Comment: CGM useful for detecting unrecognized hypoglycemias in type 1 and type 2 diabetic subjects; but not better than standard capillary glucose measurements for improving metabolic control of type 1 diabetic subjects.
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