COVID-19 Vaccines

VACCINE TYPE

• Three COVID-19 vaccines are commercially available for use. The CDC does not recommend one particular product over another.
  • The Pfizer-BioNTech vaccine is a lipid nanoparticle-formulated, nucleoside-modified RNA (mRNA) vaccine encoding a prefusion-stabilized, membrane-anchored SARS-CoV-2 spike protein.
  • The Moderna COVID-19 vaccine (mRNA-1273) is a lipid nanoparticle-encapsulated, nucleoside-modified messenger RNA vaccine that encodes the SARS-CoV-2 spike glycoprotein.
  • The Novavax COVID-19 vaccine (NVX-CoV2373) is an adjuvanted vaccine containing purified, full-length rS protein. The vaccine elicits an immune response to this protein, leading to protection against COVID-19.
• In the fall of 2025, the CDC updated COVID-19 vaccine recommendations to include all patients 6 months and older receiving an updated COVID-19 2025-26 vaccine, based on individual shared decision-making with their provider. These vaccines are currently available for use.
  • High-risk patients include those aged 65 and older, those living in a long-term care facility, and those who are pregnant and/or breastfeeding.