Lefamulin

Fidelia Bernice, Pharm.D.
Pediatric Dosing Author: Bethany Sharpless Chalk, Pharm.D., BCPPS
Lefamulin is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

  • Treatment of community-acquired pneumonia caused by susceptible organisms.
    • Streptococcus pneumoniae, methicillin-susceptible Staphylococcus aureus, Haemophilus influenzae,Legionella pneumophila, Mycoplasma pneumoniae, and Chlamydophila pneumoniae.

NON-FDA APPROVED USES

  • In vitro activity has been demonstrated against methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecium, multidrug-resistant Neisseria gonorrhoeae, and Mycoplasma genitalium.

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INDICATIONS

FDA

  • Treatment of community-acquired pneumonia caused by susceptible organisms.
    • Streptococcus pneumoniae, methicillin-susceptible Staphylococcus aureus, Haemophilus influenzae,Legionella pneumophila, Mycoplasma pneumoniae, and Chlamydophila pneumoniae.

NON-FDA APPROVED USES

  • In vitro activity has been demonstrated against methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecium, multidrug-resistant Neisseria gonorrhoeae, and Mycoplasma genitalium.

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