Daclatasvir

Janessa M. Smith, PharmD, BCPS
Daclatasvir is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

  • Treatment of chronic hepatitis C virus (HCV) genotype 1 or 3 infection, in combination with sofosbuvir (SOF).
    • Daclatasvir is indicated for treatment of HIV/HCV co-infected patients, in patients with compensated Child-Pugh Class A cirrhosis, decompensated Child-Pugh B or C cirrhosis and in patients that develop recurrent HCV post-transplant.

NON-FDA APPROVED USES

Treatment of HCV genotypes 2, 4.

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INDICATIONS

FDA

  • Treatment of chronic hepatitis C virus (HCV) genotype 1 or 3 infection, in combination with sofosbuvir (SOF).
    • Daclatasvir is indicated for treatment of HIV/HCV co-infected patients, in patients with compensated Child-Pugh Class A cirrhosis, decompensated Child-Pugh B or C cirrhosis and in patients that develop recurrent HCV post-transplant.

NON-FDA APPROVED USES

Treatment of HCV genotypes 2, 4.

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