Ceftolozane/tazobactam
Ceftolozane/tazobactam is a topic covered in the Johns Hopkins ABX Guide.
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INDICATIONS
FDA
FDA
- Ceftolozane/tazobactam is currently on manufacturer backorder. Per communication from Merck, the drug is not expected to be released until early 2022.
- Alternative therapies for MDR Pseudomonas aeruginosashould be considered.
- Complicated intra-abdominal infections (cIAI), used in combination with metronidazole
- Complicated urinary tract infections (cUTI), including pyelonephritis
- Hospital-acquired bacterial and ventilator-associated pneumonia (VAP)
Note: FDA indications for age ≥ 18 yrs
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Pseudomonas aeruginosa infections (including some MDR isolates, limited data[6])
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INDICATIONS
FDA
FDA
- Ceftolozane/tazobactam is currently on manufacturer backorder. Per communication from Merck, the drug is not expected to be released until early 2022.
- Alternative therapies for MDR Pseudomonas aeruginosashould be considered.
- Complicated intra-abdominal infections (cIAI), used in combination with metronidazole
- Complicated urinary tract infections (cUTI), including pyelonephritis
- Hospital-acquired bacterial and ventilator-associated pneumonia (VAP)
Note: FDA indications for age ≥ 18 yrs
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Pseudomonas aeruginosa infections (including some MDR isolates, limited data[6])
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