CNS Shunt Infections

Paul Auwaerter, M.D.
CNS Shunt Infections is a topic covered in the Johns Hopkins ABX Guide.

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PATHOGENS

Commonly implicated pathogens:

  • Coagulase-negative staphylococci
  • S. aureus
  • Streptococcal species
  • Gram-negative bacteria
  • Propionibacterium species
  • Corynebacterium spp.
  • Candida species
  • The vast majority of CSF shunt infections are caused by normal skin commensals.
    • Coagulase-negative staphylococci 40-45%, S. aureus 25%, C. acnes less common (usually less than 8% most series), Corynebacteria/diphtheroids (rare).
      • Biofilm formation likely important role in many infections.
  • Patients with CSF shunts have an increased risk of meningitis caused by traditional pathogens (S. pneumoniae, N. meningitidis, H. influenzae), these are often treatable without shunt revision.

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PATHOGENS

Commonly implicated pathogens:

  • Coagulase-negative staphylococci
  • S. aureus
  • Streptococcal species
  • Gram-negative bacteria
  • Propionibacterium species
  • Corynebacterium spp.
  • Candida species
  • The vast majority of CSF shunt infections are caused by normal skin commensals.
    • Coagulase-negative staphylococci 40-45%, S. aureus 25%, C. acnes less common (usually less than 8% most series), Corynebacteria/diphtheroids (rare).
      • Biofilm formation likely important role in many infections.
  • Patients with CSF shunts have an increased risk of meningitis caused by traditional pathogens (S. pneumoniae, N. meningitidis, H. influenzae), these are often treatable without shunt revision.

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