CNS Shunt Infections
CNS Shunt Infections is a topic covered in the Johns Hopkins ABX Guide.
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PATHOGENS
- Coagulase-negative staphylococci
- S. aureus
- Streptococcal species
- Gram-negative bacteria
- Propionibacterium species
- Corynebacterium spp.
- Candida species
- Vast majority CSF shunt infections caused by normal skin commensals.
- Coagulase-negative staphylococci 40-45%, S. aureus 25%. P. acnes uncommon (usually less than 8% most series), diphtheroids (rare).
- Biofilm formation likely important role in many infections.
- Patients with CSF shunts have an increased risk of meningitis caused by traditional pathogens (S. pneumoniae, N. meningitidis, H. influenzae), these are often treatable without shunt revision.
- Coagulase-negative staphylococci 40-45%, S. aureus 25%. P. acnes uncommon (usually less than 8% most series), diphtheroids (rare).
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