Parainfluenza virus

Paul G. Auwaerter, M.D.

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MICROBIOLOGY

RNA enveloped (single strand, negative sense) virus w/ 5 antigenically distinct types: human parainfluenza virus types HPIV, HPIV-1, HPIV-2, HPIV-3, HPIV-4A/4B.
Viruses are members of the paramyxovirus family with two different genera:
- HPIV-1, HPIV-3 belong to the Respirovirus genus.
  - HPIV-1: cause of croup in children with tendency to see more cases in fall season of odd-numbered years.
  - HPIV-3: cause of respiratory infections year-round especially when HPIV-1 and HPIV-2 not especially active, but more often seen in spring and early summer.
- HPIV-2, HPIV-4 belong to the Rubulavirus genus.
  - HPIV-2: cause of croup in children, less common than HPIV-1 or HPIV-3, most cases seen in fall yearly.
  - HPIV-4: patterns are not well characterized.

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MICROBIOLOGY

RNA enveloped (single strand, negative sense) virus w/ 5 antigenically distinct types: human parainfluenza virus types HPIV, HPIV-1, HPIV-2, HPIV-3, HPIV-4A/4B.
Viruses are members of the paramyxovirus family with two different genera:
- HPIV-1, HPIV-3 belong to the Respirovirus genus.
  - HPIV-1: cause of croup in children with tendency to see more cases in fall season of odd-numbered years.
  - HPIV-3: cause of respiratory infections year-round especially when HPIV-1 and HPIV-2 not especially active, but more often seen in spring and early summer.
- HPIV-2, HPIV-4 belong to the Rubulavirus genus.
  - HPIV-2: cause of croup in children, less common than HPIV-1 or HPIV-3, most cases seen in fall yearly.
  - HPIV-4: patterns are not well characterized.

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