Oral Candidiasis

Shmuel Shoham, M.D.

PATHOGENS

Candida albicans
- This is the dominant organism in oral candidiasis (~80% of colonizing isolates).
  - C. albicans may cause infection alone or in combination with non-C. albicans species.
- Typically susceptible to azole antifungals, but resistance can develop.
Non-albicans Candida spp
- Most common non-C. albicans organisms: C. glabrata,C. tropicalis, C. dubliniensis and C. krusei.
- C. glabrata may occur as part of a mixed infection (along with C. albicans) and can cause fluconazole refractory infections, some of which can prove resistant to other azoles as well.

There's more to see -- the rest of this topic is available only to subscribers.