Mumps

Paul Auwaerter, M.D.
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MICROBIOLOGY

  • Paramyxovirus (Rubulavirus, order Mononegavirales, negative-sense, single-strand RNA) spread by respiratory transmission
    • Enveloped virus with structure and non-structural proteins
      • Hemagglutinin-neuraminidase (HN)and fusion (F) proteins required for cellular entry and budding
      • Epithelial cells, parotid, salivary glands infected; ependymal cells in CNS.

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MICROBIOLOGY

  • Paramyxovirus (Rubulavirus, order Mononegavirales, negative-sense, single-strand RNA) spread by respiratory transmission
    • Enveloped virus with structure and non-structural proteins
      • Hemagglutinin-neuraminidase (HN)and fusion (F) proteins required for cellular entry and budding
      • Epithelial cells, parotid, salivary glands infected; ependymal cells in CNS.

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