Mumps

Paul Auwaerter, M.D.

Mumps is a topic covered in the Johns Hopkins ABX Guide.

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MICROBIOLOGY

Paramyxovirus (Rubulavirus, order Mononegavirales, negative-sense, single-strand RNA) spread by respiratory transmission
- Enveloped virus with structure and non-structural proteins
  - Hemagglutinin-neuraminidase (HN)and fusion (F) proteins required for cellular entry and budding
  - Epithelial cells, parotid, salivary glands infected; ependymal cells in CNS.

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MICROBIOLOGY

Paramyxovirus (Rubulavirus, order Mononegavirales, negative-sense, single-strand RNA) spread by respiratory transmission
- Enveloped virus with structure and non-structural proteins
  - Hemagglutinin-neuraminidase (HN)and fusion (F) proteins required for cellular entry and budding
  - Epithelial cells, parotid, salivary glands infected; ependymal cells in CNS.

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