Metronidazole
Metronidazole is a topic covered in the Johns Hopkins ABX Guide.
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INDICATIONS
FDA
FDA
- Anaerobic infections: intra-abdominal infections, skin and skin structure infections, bone and joint infections
- Bacterial septicemia; endocarditis (caused by Bacteroides spp.)
- Gynecologic infections (endometritis, endomyometritis, tubo-ovarian abscess, and postsurgical vaginal cuff infection) in combination with agents active against Gram-negative urogenital flora.
- Lower respiratory tract infections (in combination with another agent with activity against microaerophilic Streptococcus)
- Adjunct treatment for gastritis and duodenal ulcer associated with Helicobacter pylori
- CNS infections (meningitis and brain abscess)
- Treatment of acute intestinal amebiasis and amebic liver abscess
- Treatment of symptomatic and asymptomatic trichomoniasis
- Bacterial vaginosis (vaginal gel)
- Acne rosacea (topical gel)
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Colitis, including C. difficile, Crohn’s flare
- Treatment of giardiasis and dracunculiasis
- Periodontal disease
- Elective colorectal surgery (classified as contaminated or potentially contaminated)
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INDICATIONS
FDA
FDA
- Anaerobic infections: intra-abdominal infections, skin and skin structure infections, bone and joint infections
- Bacterial septicemia; endocarditis (caused by Bacteroides spp.)
- Gynecologic infections (endometritis, endomyometritis, tubo-ovarian abscess, and postsurgical vaginal cuff infection) in combination with agents active against Gram-negative urogenital flora.
- Lower respiratory tract infections (in combination with another agent with activity against microaerophilic Streptococcus)
- Adjunct treatment for gastritis and duodenal ulcer associated with Helicobacter pylori
- CNS infections (meningitis and brain abscess)
- Treatment of acute intestinal amebiasis and amebic liver abscess
- Treatment of symptomatic and asymptomatic trichomoniasis
- Bacterial vaginosis (vaginal gel)
- Acne rosacea (topical gel)
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Colitis, including C. difficile, Crohn’s flare
- Treatment of giardiasis and dracunculiasis
- Periodontal disease
- Elective colorectal surgery (classified as contaminated or potentially contaminated)
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