Ketoconazole
Ketoconazole is a topic covered in the Johns Hopkins ABX Guide.
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INDICATIONS
FDA
FDA
- Systemic
- Treatment of blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.
- Note: despite FDA approval, due to the potential for severe hepatitis, adrenal insufficiency, and drug-drug interactions, systemic ketoconazole should not be used as a first-line treatment for any fungal infections.
- Treatment of blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.
- Ketoconazole cream 2%
- Treatment of tinea corporis, tinea cruris and tinea pedis caused by Trichophyton rubrum, T. mentagrophytes and Epidermophyton floccosum
- Treatment of tinea (pityriasis) versicolor caused by Malassezia furfur (Pityrosporum orbiculare)
- Treatment of cutaneous candidiasis caused by Candida spp.
- Treatment of seborrheic dermatitis.
- Ketoconazole shampoo 2%
- Treatment of tinea (pityriasis) versicolor caused by or presumed to be caused by Pityrosporum orbiculare (also known as Malassezia furfur or M. orbiculare).
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Treatment of hyperadrenalism
- Booster for calcineurin inhibitor to increase levels in solid organ transplant recipients
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INDICATIONS
FDA
FDA
- Systemic
- Treatment of blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.
- Note: despite FDA approval, due to the potential for severe hepatitis, adrenal insufficiency, and drug-drug interactions, systemic ketoconazole should not be used as a first-line treatment for any fungal infections.
- Treatment of blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.
- Ketoconazole cream 2%
- Treatment of tinea corporis, tinea cruris and tinea pedis caused by Trichophyton rubrum, T. mentagrophytes and Epidermophyton floccosum
- Treatment of tinea (pityriasis) versicolor caused by Malassezia furfur (Pityrosporum orbiculare)
- Treatment of cutaneous candidiasis caused by Candida spp.
- Treatment of seborrheic dermatitis.
- Ketoconazole shampoo 2%
- Treatment of tinea (pityriasis) versicolor caused by or presumed to be caused by Pityrosporum orbiculare (also known as Malassezia furfur or M. orbiculare).
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Treatment of hyperadrenalism
- Booster for calcineurin inhibitor to increase levels in solid organ transplant recipients
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