Japanese Encephalitis Virus

Lisa A. Spacek, M.D., Ph.D.
Japanese Encephalitis Virus is a topic covered in the Johns Hopkins ABX Guide.

To view the entire topic, please or .

Official website of the Johns Hopkins Antibiotic (ABX), HIV, Diabetes, and Psychiatry Guides, powered by Unbound Medicine. Johns Hopkins Guide App for iOS, iPhone, iPad, and Android included. Explore these free sample topics:

-- The first section of this topic is shown below --

MICROBIOLOGY

  • Japanese encephalitis virus (JEV): mosquito-borne flavivirus, similar to St. Louis encephalitis virus, Murray Valley encephalitis, yellow fever, dengue, and West Nile virus.
  • Single-stranded, positive-sense RNA virus.
  • JEV is transmitted by Culex mosquitoes or species that lay eggs in flooded rice fields.
    • Wild birds are natural hosts, and domestic pigs and birds are amplifying hosts. Bats transmit disease in China.
    • Blood transfusion and organ transplantation are potential modes of transmission.
  • JEV is endemic in Asia, Southeast Asia, and the Pacific islands causing about 70,000 cases of infection and 14,000-20,000 deaths per year worldwide.[11]
    • Map of JE transmission
    • Risk of infection estimated at 1/5000 per month of travel to rural areas of Asia where transmission occurs.
    • In temperate Asia, the incidence of cases peaks in summer and fall.
    • In tropics or subtropics, transmission occurs in wet seasons but may occur year-round.
    • Emerging risk in southern Europe via C. pipiens with JEV sequences found in mosquitoes and birds in Italy.[5]

-- To view the remaining sections of this topic, please or --

MICROBIOLOGY

  • Japanese encephalitis virus (JEV): mosquito-borne flavivirus, similar to St. Louis encephalitis virus, Murray Valley encephalitis, yellow fever, dengue, and West Nile virus.
  • Single-stranded, positive-sense RNA virus.
  • JEV is transmitted by Culex mosquitoes or species that lay eggs in flooded rice fields.
    • Wild birds are natural hosts, and domestic pigs and birds are amplifying hosts. Bats transmit disease in China.
    • Blood transfusion and organ transplantation are potential modes of transmission.
  • JEV is endemic in Asia, Southeast Asia, and the Pacific islands causing about 70,000 cases of infection and 14,000-20,000 deaths per year worldwide.[11]
    • Map of JE transmission
    • Risk of infection estimated at 1/5000 per month of travel to rural areas of Asia where transmission occurs.
    • In temperate Asia, the incidence of cases peaks in summer and fall.
    • In tropics or subtropics, transmission occurs in wet seasons but may occur year-round.
    • Emerging risk in southern Europe via C. pipiens with JEV sequences found in mosquitoes and birds in Italy.[5]

There's more to see -- the rest of this entry is available only to subscribers.