Prosthetic Joint Infections
Prosthetic Joint Infections is a topic covered in the Johns Hopkins ABX Guide.
To view the entire topic, please log in or purchase a subscription.
Official website of the Johns Hopkins Antibiotic (ABX), HIV, Diabetes, and Psychiatry Guides, powered by Unbound Medicine. Johns Hopkins Guide App for iOS, iPhone, iPad, and Android included. Explore these free sample topics:
-- The first section of this topic is shown below --
PATHOGENS
- Staphylococci account for >50% of total prosthetic joint infections (PJI). Gram-negatives may account for 15%. Approximately 20% may be polymicrobial.
- Culture-negative infections represent ~7-11% of infections; some may be due to prior abx therapy.
- Bacterial:
- Staphylococcus (coagulase-negative)
- Staphylococcus aureus
- Viridans streptococci
- Cutibacterium acnes (especially shoulder implant infections, formerly Propionibacterium)
- Enterococcal species
- Gram-negative enteric bacteria
- Pseudomonas aeruginosa
- Anaerobes
- Brucella spp (rare)
- Mycobacterial:
- Non-tubercular mycobacteria (rare)
- M. tuberculosis (very rare)
- Fungal:
- Candida species
- Typical pathogens by the time of onset following prosthesis placement:
- Early infection (0-3 months post-op): predominantly S. aureus, β-hemolytic streptococci, Gram-negative bacilli, polymicrobial infection, anaerobic
- Delayed (3 mos-2 yrs): usual pathogens include coagulase-negative Staphylococci,S. aureus,C. acnes, Enterococcus spp.
- Late (>2 yrs): S. aureus, coagulase-negative Staphylococci, viridans Streptococci, Enterococci, C. acnes
- Less common: Gram-negatives
-- To view the remaining sections of this topic, please log in or purchase a subscription --
PATHOGENS
- Staphylococci account for >50% of total prosthetic joint infections (PJI). Gram-negatives may account for 15%. Approximately 20% may be polymicrobial.
- Culture-negative infections represent ~7-11% of infections; some may be due to prior abx therapy.
- Bacterial:
- Staphylococcus (coagulase-negative)
- Staphylococcus aureus
- Viridans streptococci
- Cutibacterium acnes (especially shoulder implant infections, formerly Propionibacterium)
- Enterococcal species
- Gram-negative enteric bacteria
- Pseudomonas aeruginosa
- Anaerobes
- Brucella spp (rare)
- Mycobacterial:
- Non-tubercular mycobacteria (rare)
- M. tuberculosis (very rare)
- Fungal:
- Candida species
- Typical pathogens by the time of onset following prosthesis placement:
- Early infection (0-3 months post-op): predominantly S. aureus, β-hemolytic streptococci, Gram-negative bacilli, polymicrobial infection, anaerobic
- Delayed (3 mos-2 yrs): usual pathogens include coagulase-negative Staphylococci,S. aureus,C. acnes, Enterococcus spp.
- Late (>2 yrs): S. aureus, coagulase-negative Staphylococci, viridans Streptococci, Enterococci, C. acnes
- Less common: Gram-negatives
There's more to see -- the rest of this topic is available only to subscribers.
© 2000–2022 Unbound Medicine, Inc. All rights reserved