Cefotaxime

Kathryn Dzintars, Pharm.D. BCPS, Paul A. Pham, Pharm.D.
Pediatric Dosing Author: Alice Jenh Hsu, PharmD, BCPS, AQ-ID
Cefotaxime is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

  • Lower respiratory tract infections including pneumonia
  • Genitourinary infections
  • Gynecologic infection (including pelvic inflammatory disease, endometritis, and pelvic cellulitis)
  • Bacteremia and septicemia
  • Skin and skin-structure infections
  • Intra-abdominal infections including peritonitis
  • Bone and joint infections
  • Central nervous system infections including meningitis and ventriculitis

NON-FDA APPROVED USES

  • Brain abscess (in combination with metronidazole)
  • Empyema (in combination with metronidazole)
  • Lyme disease: late Lyme arthritis and neuroborreliosis
  • STD (Neisseria gonorrhoeae)

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INDICATIONS

FDA

  • Lower respiratory tract infections including pneumonia
  • Genitourinary infections
  • Gynecologic infection (including pelvic inflammatory disease, endometritis, and pelvic cellulitis)
  • Bacteremia and septicemia
  • Skin and skin-structure infections
  • Intra-abdominal infections including peritonitis
  • Bone and joint infections
  • Central nervous system infections including meningitis and ventriculitis

NON-FDA APPROVED USES

  • Brain abscess (in combination with metronidazole)
  • Empyema (in combination with metronidazole)
  • Lyme disease: late Lyme arthritis and neuroborreliosis
  • STD (Neisseria gonorrhoeae)

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