Cefixime

Edina Avdic, Pharm.D., Paul A. Pham, Pharm.D. BCPS
Pediatric Dosing Author: Alice Jenh Hsu, PharmD, BCPS, AQ-ID
Cefixime is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

  • Otitis media caused by H. influenzae, M. catarrhalis and S. pyogenes
  • Pharyngitis and tonsillitis caused by S. pyogenes (PCN is the drug of choice)
  • Acute bronchitis and acute exacerbation of chronic bronchitis (AECB) caused by S. pneumoniae and H. influenzae (note: relatively poor S. pneumoniae activity)
  • Uncomplicated urinary tract infections caused by E. coli and P. mirabilis
  • Uncomplicated gonorrhea (cervicitis and urethritis, see NOTE under COMMENTS regarding use of cefixime for treating gonorrhea)

NON-FDA APPROVED USES

  • Sinusitis, acute (not a first line agent)
  • Prophylaxis after sexual victimization

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INDICATIONS

FDA

  • Otitis media caused by H. influenzae, M. catarrhalis and S. pyogenes
  • Pharyngitis and tonsillitis caused by S. pyogenes (PCN is the drug of choice)
  • Acute bronchitis and acute exacerbation of chronic bronchitis (AECB) caused by S. pneumoniae and H. influenzae (note: relatively poor S. pneumoniae activity)
  • Uncomplicated urinary tract infections caused by E. coli and P. mirabilis
  • Uncomplicated gonorrhea (cervicitis and urethritis, see NOTE under COMMENTS regarding use of cefixime for treating gonorrhea)

NON-FDA APPROVED USES

  • Sinusitis, acute (not a first line agent)
  • Prophylaxis after sexual victimization

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