Bacterial Cystitis, Acute, Uncomplicated

Michael Melia, M.D.
Bacterial Cystitis, Acute, Uncomplicated is a topic covered in the Johns Hopkins ABX Guide.

To view the entire topic, please log in or purchase a subscription.

Official website of the Johns Hopkins Antibiotic (ABX), HIV, Diabetes, and Psychiatry Guides, powered by Unbound Medicine. Johns Hopkins Guide App for iOS, iPhone, iPad, and Android included. Explore these free sample topics:

Johns Hopkins Guides

COVID-19 Update with Dr. Paul Auwaerter of Johns Hopkins : Omicron Variant, Testing, and TreatmentCOVID-19 Update with Dr. Paul Auwaerter of Johns Hopkins : Omicron Variant, Testing, and Treatment

Coronavirus COVID-19 (SARS-CoV-2)Coronavirus COVID-19 (SARS-CoV-2)

Suicide Risk in the COVID-19 PandemicSuicide Risk in the COVID-19 Pandemic

Moderna COVID-19 VaccineModerna COVID-19 Vaccine

BNT162b2 COVID-19 Vaccine (BioNTech/Pfizer)BNT162b2 COVID-19 Vaccine (BioNTech/Pfizer)

Managing Stress and Coping with COVID-19Managing Stress and Coping with COVID-19

Johnson & Johnson COVID-19 VaccineJohnson & Johnson COVID-19 Vaccine

-- The first section of this topic is shown below --

PATHOGENS

  • Uncomplicated UTI: >95% of these infections are due to single organism.
  • Culprit pathogens:
    • E. coli (75-95%)
      • Uropathogenic E. coli (UPEC) most likely to cause UTIs are groups B2 and D that have "fitness elements" providing them with advantage in extraintestinal niche.
    • Other Enterobacteriaceae (e.g., K. pneumoniae, P. mirabilis)
    • S. saprophyticus 
    • Uncommon pathogens: P. aeruginosa, Group D Streptococci
    • Rare pathogens: H. influenzae, M. tuberculosis, anaerobes, Salmonella, Shigella, adenovirus type 11, Ureaplasma, Mycoplasma, Enterococcus spp., Group B Streptococci
      • Enterococcus spp. and group B Streptococcus alone rarely cause uncomplicated cystitis (see excellent Hooton NEJM 2013 reference[3]).
        • These two organisms are recovered from midstream urine specimens of ~10% of women with cystitis, but are rarely (1%) also isolated from paired catheter urine specimens.

-- To view the remaining sections of this topic, please log in or purchase a subscription --

PATHOGENS

  • Uncomplicated UTI: >95% of these infections are due to single organism.
  • Culprit pathogens:
    • E. coli (75-95%)
      • Uropathogenic E. coli (UPEC) most likely to cause UTIs are groups B2 and D that have "fitness elements" providing them with advantage in extraintestinal niche.
    • Other Enterobacteriaceae (e.g., K. pneumoniae, P. mirabilis)
    • S. saprophyticus 
    • Uncommon pathogens: P. aeruginosa, Group D Streptococci
    • Rare pathogens: H. influenzae, M. tuberculosis, anaerobes, Salmonella, Shigella, adenovirus type 11, Ureaplasma, Mycoplasma, Enterococcus spp., Group B Streptococci
      • Enterococcus spp. and group B Streptococcus alone rarely cause uncomplicated cystitis (see excellent Hooton NEJM 2013 reference[3]).
        • These two organisms are recovered from midstream urine specimens of ~10% of women with cystitis, but are rarely (1%) also isolated from paired catheter urine specimens.

There's more to see -- the rest of this entry is available only to subscribers.

© 2000–2022 Unbound Medicine, Inc. All rights reserved