Atovaquone + Proguanil
Y. Vivian Tsai, Pharm.D., Kathryn Dzintars, Pharm.D., BCPS
INDICATIONS
INDICATIONS
INDICATIONS
FDA
FDA
- Chemoprophylaxis of P. falciparum malaria, including in areas where chloroquine resistance has been reported.[1][17]
- Treatment of acute, uncomplicated P. falciparum malaria.[17]
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Chemoprophylaxis in all malaria-endemic areas (not limited to P. falciparum).[1]
- Severe malaria—atovaquone/proguanil is not primary definitive therapy
- Can be considered as initial oral bridge therapy to IV artesunate if IV artesunate not immediately available.
- As an alternative complete follow-on oral regimen after IV artesunate once parasitemia ≤1%.
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