Johns Hopkins Guides provide diagnosis, management, and treatment guidance for infectious diseases, diabetes, and psychiatric conditions. Explore these free sample topics:
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- Pathoplasticity is the “variability in a symptom’s specific form and content, shaped by events in a patient’s life.” 
- Pathoplastic features are differentiated from pathognomonic features, which are specifically distinctive or characteristic of a disease or pathologic condition.
- The clinician can make a diagnosis based on pathognomonic signs and symptoms, but pathoplastic features by definition can vary between individuals with the same diagnosis.