Trimethoprim + Sulfamethoxazole is a topic covered in the Johns Hopkins HIV Guide.

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INDICATIONS

FDA

  • Acute exacerbation of chronic bronchitis
  • Otitis media (in S. pneumoniae sensitive cases only)
  • PCP prophylaxis
  • PCP treatment
  • Traveler’s diarrhea, shigellosis
  • Urinary tract infections

NON-FDA APPROVED USES

  • Nocardia infection
  • Toxoplasmosis treatment and prophylaxis
  • Bacterial cystitis prophylaxis
  • Isospora infections
  • Salmonella infections
  • MSSA and community-acquired MRSA soft tissue infections
  • Legionellosis treatment (2nd line)
  • Listeriosis treatment (2nd line for PCN allergic pts)

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Last updated: December 22, 2011