Posaconazole is a topic covered in the Johns Hopkins HIV Guide.

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INDICATIONS

FDA

  • Prophylaxis of invasive aspergillosis and disseminated candidiasis in severely immunocompromised hosts, such as hemapoietic stem cell transplant recipients with graft vs. host (GVH) disease or those with hematologic malignancies with prolonged neutropenia from chemotherapy.
  • Treatment of oropharyngeal candidiasis, including itraconazole and/or fluconazole-refractory cases.

NON-FDA APPROVED USES

  • Treatment of invasive fungal infections due to Aspergillus spp., Candida spp., and zygomycoses (e.g., Rhizomucor, Cunnighamella, Absidia species).

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Last updated: November 9, 2011