Penicillium marneffei is a topic covered in the Johns Hopkins HIV Guide.

To view the entire topic, please or purchase a subscription.

Johns Hopkins Guides provide diagnosis, management, and treatment guidance for infectious diseases, diabetes, and psychiatric conditions. Explore these free sample topics:

Johns Hopkins Guides

~~ The first section of this topic is shown below ~~

MICROBIOLOGY

  • Dimorphic fungus, recent taxonomy change to Talaromyces from Penicillium subgenus Biverticillium, reflects phylogenetic distinction from other subgenera of Penicillium.
    • Mold at 25oC with short, hyaline, septate and branched hyphae;
    • Yeast at 37oC with cerebriform, smooth, light tan colonies; secretes bright red pigment that appears pink as it diffuses into agar.
      • Yeast form 3-6 x 2 µm, sausage-shaped with central transverse septum.
  • Reservoir: Bamboo rats
    • T. marneffei geographically distributed across tropical SE Asia. [5]
    • Found in 100% of sample of hoary bamboo rats (cultured from lungs, liver and spleen) in Guangxi Province, China. [2]
    • Organism also isolated from soil of bamboo rats’ burrows.
  • Transmitted primarily via inhalation; also direct inoculation, possibly ingestion.
  • Endemic in: NE India, Thailand, Vietnam, Indonesia, Hong Kong, southern China.

~~ To view the remaining sections of this topic, please
or purchase a subscription ~~

Last updated: October 3, 2015