Vitamin D is a topic covered in the Johns Hopkins Diabetes Guide.

To view the entire topic, please or purchase a subscription.

Johns Hopkins Guides provide diagnosis, management, and treatment guidance for infectious diseases, diabetes, and psychiatric conditions. Explore these free sample topics:

Johns Hopkins Guides

~~ The first section of this topic is shown below ~~

DESCRIPTION

  • Estimated that over 1 billion people worldwide have vitamin D deficiency or insufficiency [14].
  • Studies ongoing to determine the prevalence of hypovitaminosis D in type 1 diabetes (T1DM) and type 2 diabetes (T2DM); preliminary data suggests prevalence may be as high as 30% in T2DM [9].
  • Vitamin D optimizes intestinal calcium and phosphorus absorption to maintain skeletal mineral content.
  • Sources of vitamin D include sunlight exposure, dietary intake, dietary supplements.
  • Vitamin D derived from sunlight or dietary sources metabolized in the liver to form 25-hydroxyvitamin D (25(OH)D)
  • 25-hydroxyvitamin D metabolized by 1-alpha-hydroxylase in kidneys to active form, 1,25-dihydroxyvitamin D (1,25(OH)D)
  • Vitamin D deficiency in adults can lead to development of osteopenia, osteoporosis, and/or osteomalacia; muscle weakness; and increased risk of fractures and falls.
  • Vitamin D may have other roles in human health including modulation of immune function and reduction of inflammation, though studies are ongoing.

~~ To view the remaining sections of this topic, please
or purchase a subscription ~~

Last updated: March 25, 2013