Johns Hopkins Guides provide diagnosis, management, and treatment guidance for infectious diseases, diabetes, and psychiatric conditions. Explore these free sample topics:
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- Diabetic foot ulcer (DFU): A non-healing or poorly healing full-thickness wound, through the dermis, below the ankle in an individual with diabetes, critical in the natural history of the diabetic foot.  
- DFUs are categorized as being purely neuropathic, purely ischemic or neuroischemic (mixed).
- Most common sites: plantar surface of foot (metatarsal heads and midfoot), toes (dorsal interphalangeal joints or distal tip).
- Pathogenesis: DFUs frequently caused by repetitive injury to an insensate or dysvascular foot.