Diabetic Ketoacidosis is a topic covered in the Johns Hopkins Diabetes Guide.

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DEFINITION

  • A metabolic acidosis characterized by the triad of hyperglycemia (glucose >250 mg/dL), metabolic acidosis (arterial pH ≤ 7.3, serum bicarbonate ≤ 18 meq/L) and moderate ketonuria or ketonemia
  • Most, but not all, patients have type 1 diabetes
  • Patients with type 2 diabetes also susceptible during acute illness (especially of African American or Hispanic descent) referred to as "ketosis-prone type 2 diabetes," likely due to greater relative insulinopenia [7].

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Last updated: November 5, 2015