Powassan virus is a topic covered in the Johns Hopkins Antibiotic (ABX) Guide.

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MICROBIOLOGY

  • Flavivirus, positive strand RNA virus.
    • Tick-borne encephalitis group
    • Two lineages: can only be distinguished by molecular techniques, both capable of causing human infection.
      • Powassan virus prototype (POWV lineage 1): enzootic cycle with tick Ixodes cookei and groundhogs or skunks.
      • Deer tick virus (DTV, or POWV lineage 2): enzootic cycle between Ixodes scapularis and white-footed mice, same as Lyme disease.

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Last updated: March 2, 2016