Johns Hopkins Antibiotic (ABX) GuideBrand Names

Artemether/Lemefantrine

Alice M. Jenh, PharmD, Paul A. Pham, PharmD
Artemether/Lemefantrine is a topic covered in the Johns Hopkins Antibiotic (ABX) Guide.

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INDICATIONS

FDA

  • Falciparum malaria, uncomplicated disease in geographic areas of known chloroquine resistance.
    • Not approved for patients with severe or complicated P. falciparum malaria.
  • Not approved for the prevention of malaria.

NON-FDA APPROVED USES

  • Vivax malaria: Limited efficacy observed in one Thai study: rapid parasite clearance observed with 4-dose regimen, relapse was common, suggesting minimal activity against the hypnozoite stage of P. vivax [4].

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Last updated: June 27, 2014