Cefotetan is a topic covered in the Johns Hopkins Antibiotic (ABX) Guide.

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INDICATIONS

FDA

  • Urinary tract infections
  • Lower respiratory tract infections
  • Skin and skin-structure infections
  • Gynecologic infections including PID (note: no activity against C. trachomatis)
  • Intra-abdominal infections (IDSA guidelines: cefotetan is no longer recommended for intra-abdominal infections as monotherapy due to high rates of B. fragilis resistance).
  • Bone and joint infections (author’s comment: generally used for mild infections)
  • Surgical prophylaxis (e.g., cesarean section, abdominal or vaginal hysterectomy, trans-urethral surgery, biliary tract surgery, and gastrointestinal surgery)

NON-FDA APPROVED USES

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Last updated: June 21, 2016