Johns Hopkins Antibiotic (ABX) GuideDiagnosisGenitourinary

Bacterial Cystitis, Acute, Uncomplicated

Michael Melia, M.D.
Bacterial Cystitis, Acute, Uncomplicated is a topic covered in the Johns Hopkins Antibiotic (ABX) Guide.

To view the entire topic, please or purchase a subscription.

Johns Hopkins Guides provide diagnosis, management, and treatment guidance for infectious diseases, diabetes, and psychiatric conditions. Explore these free sample topics:

Johns Hopkins Guides

~~ The first section of this topic is shown below ~~

PATHOGENS

  • Uncomplicated UTI: >95% of these infections are due to single organism.
  • Culprit pathogens:
    • E. coli (75-95%)
      • Uropathogenic E. coli (UPEC) most likely to cause UTIs are groups B2 and D that have "fitness elements" providing them with advantage in extraintestinal niche.
    • Other Enterobacteriaceae (e.g., K. pneumoniae, P. mirabilis)
    • S. saprophyticus 
    • Uncommon pathogens: P. aeruginosa, Group D Streptococci
    • Rare pathogens: H. influenzae, M. tuberculosis, anaerobes, Salmonella, Shigella, adenovirus type 11, Ureaplasma, Mycoplasma, Enterococcus spp., Group B Streptococci
      • Enterococcus spp. and group B Streptococcus alone rarely cause uncomplicated cystitis (see excellent Hooton NEJM 2013 reference [15])
        • These two organisms are recovered from midstream urine specimens of ~10% of women with cystitis, but are rarely (1%) also isolated from paired catheter urine specimens

~~ To view the remaining sections of this topic, please
or purchase a subscription ~~

Last updated: July 1, 2016