Johns Hopkins HIV Guide

Microsporidiosis

Khalil Ghanem, M.D.; Lisa A. Spacek, M.D., Ph.D.

PATHOGENS

  • Microsporidia are protists related to fungi, not parasites.
  • Five genera (Enterocytozoon, Encephalitozoon, Septata, Pleistophora, & Nosema), as well as unclassified microsporidial organisms may be associated with human disease. The first two genera listed are the most frequently encountered.
  • Sources of infection & modes of transmissi, likely zoonotic and/or waterborne.
  • Spores are quite resistant to environmental conditions and can remain infectious for several years, particularly if protected from desiccation.

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