Johns Hopkins Antibiotic (ABX) Guide

Streptococcus pyogenes (Group A)

MICROBIOLOGY

  • Group A Streptococcus (GAS), beta-hemolytic--grows on blood agar, best in anaerobic conditions.
  • Gram-positive cocci in chains.
  • Ecologic niche is pharynx. 2-3% of adults colonized, 15-20% school children.
  • Virulence depends on proteins that represent toxins, mimic host macromolecules and after immune responses.

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