Mycobacterium avium-complex (MAC, MAI, non-HIV) is a topic covered in the Johns Hopkins Antibiotic (ABX) Guide.

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MICROBIOLOGY

  • M. avium and M. intracellulare are slow growing mycobacteria (10-21 days on solid media).
  • M. intracellulare is principally causes pulmonary disease. M. avium principally causes disseminated disease (among immunocompromised people).
  • Environmental sources, especially water, are the reservoir for most human infections.

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