Johns Hopkins Antibiotic (ABX) Guide

Acanthamoeba

MICROBIOLOGY

  • Acanthamoeba spp (>20 species) most prevalent protozoa; 1 of 4 genera associated with disease: Acanthamoeba spp, Naegleria fowleri, Balamuthia mandrillaris and Sappinia diploidea.
  • 2 stage life cycle: 1) actively feeding & dividing trophozoite; 2) dormant cyst (double-walled wrinkled cyst) which are resistant to chlorine and antibiotics. Encystation occurs under stress.

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