MEDLINE Journals

    Treatment of herpetic keratitis with acyclovir: benefits and problems.

    Authors

    Ohashi Y 

    Institution

    Department of Ophthalmology, Ehime University School of Medicine, Japan.

    Source

    Ophthalmologica 1997.:29-32.

    Abstract

    Since the introduction of acyclovir in the last decade, the visual prognosis of herpetic keratitis has improved dramatically. Benefits with this superb agent include rapid resolution of epithelial keratitis, reduction of disturbances in ocular surface epithelia, and a decreased incidence of necrotizing keratitis or subsequent corneal melting. On the other hand, persistent superficial punctate keratopathy associated with topical usage, emergence of an acyclovir-resistant strain of herpes simplex virus, and a gradual increase in progressive corneal endotheliitis comprise the problems to be resolved.

    Mesh

    Acyclovir
    Administration, Topical
    Animals
    Antiviral Agents
    Cornea
    Humans
    Keratitis, Herpetic
    Ophthalmic Solutions
    Prognosis
    Simplexvirus
    Visual Acuity

    Language

    eng

    Pub Type(s)

    Journal Article Review

    PubMed ID

    9065935

    Content Manager
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