Group A streptococcal infections.

Authors

Langlois DM, Andreae M 

Institution

Division of General Pediatrics, Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, MI, USA.

Source

Pediatr Rev 2011 Oct; 32(10) :423-9; quiz 430.

Abstract

• GAS is a common cause of upper respiratory tract and skin infections.• Based on strong research evidence, (1) throat culture is the gold standard for diagnosing GAS pharyngitis.• Based on strong research evidence, (1) oral penicillin V K is the antibiotic treatment of choice for GAS pharyngitis because of its efficacy, safety, and narrow spectrum.• Based on strong research evidence, (2) primary prevention of complications of GAS such as ARF involves prompt diagnosis and antibiotic treatment of GAS pharyngitis.• GAS nonsuppurative and suppurative complications may occur and are mediated by interactions between GAS antigens or exotoxins and the patient’s immunesystem.

Mesh

Anti-Bacterial Agents
Child
Fasciitis, Necrotizing
Humans
Pharyngitis
Rheumatic Fever
Shock, Septic
Skin Diseases, Bacterial
Streptococcal Infections
Streptococcus pyogenes

Language

eng

Pub Type(s)

Journal Article

PubMed ID

21965709