Mizuno S, Zendejas IR, Reed AI, et al.
Division of Transplantation and Hepatobiliary Surgery, Department of Surgery, University of Florida College of Medicine, PO Box 100286, Gainesville, FL 32610-0286, United States.
SourceWorld J Gastroenterol 2007 Aug 28; 13(32)
Listeria monocytogene is a well-recognized cause of bacteremia in immunocompromised individuals, including solid organ transplant recipients, but has been rarely reported following orthotopic liver transplantation. We describe a case of listeria meningitis that occurred within a week after liver transplantation. The patient developed a severe headache that mimicked tacrolimus encephalopathy, and was subsequently diagnosed with listeria meningitis by cerebrospinal fluid culture. The infection was successfully treated with three-week course of intravenous ampicillin. Recurrent hepatitis C followed and was successfully treated with interferon alfa and ribavirin. Fourteen cases of listeriosis after orthotopic liver transplantation have been reported in the English literature. Most reported cases were successfully treated with intravenous ampicillin. There were four cases of listeria meningitis, and the mortality of them was 50%. Early detection and treatment of listeria meningitis are the key to obtaining a better prognosis.
MeshAmpicillinAnti-Bacterial AgentsCentral Nervous SystemHumansListeria monocytogenesLiver TransplantationMaleMeningitis, ListeriaMiddle Aged
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