Escalante A, Stimmler MM
Arthritis Service, Rancho Los Amigos Medical Center, Downey, CA.
SourceJ Rheumatol 1992 May; 19(5)
Most reports of drug induced meningitis in systemic lupus erythematosus (SLE) have implicated ibuprofen. We describe a 46-year-old woman with SLE who developed aseptic meningitis abruptly after ingesting trimethoprim-sulfamethoxasole (TMP-SMX). This patient had received TMP-SMX twice before; each was associated with increasingly severe reactions, whose relationship with the use of TMP-SMX became apparent only in retrospect. A history of medication use should be sought in all patients with meningitis who have an underlying autoimmune disorder.
MeshFemaleHumansLupus Erythematosus, SystemicMeningitis, AsepticMiddle AgedTrimethoprim-Sulfamethoxazole CombinationUrinary Tract Infections
Case Reports Journal Article