Pneumococcal keratitis: a clinical profile.

Authors

Parmar P, Salman A, Kalavathy CM, et al. 

Institution

Institute of Ophthalmology, Joseph Eye Hospital, Tiruchirapalli, India. amjad26@sify.com

Source

Clin Experiment Ophthalmol 2003 Feb; 31(1) :44-7.

Abstract

AIM
To study the clinical features of pneumococcal keratitis and response to ciprofloxacin therapy.
METHODS
A retrospective analysis was undertaken of 58 patients with culture-proven pneumococcal keratitis seen over a period of 2 years.
RESULTS
Pneumococcal keratitis accounted for 33.3% of bacterial keratitis. Most cases presented with non-severe keratitis (77.5%). Co-existing sac pathology was more frequent in pneumococcal ulcers as compared to non-pneumococcal bacterial ulcers (50%vs 9%, P < 0.001). Characteristic clinical features enabling an accurate clinical diagnosis were found in 27.5% and lanceolate diplococci on Gram's stain were identified in 76% of cases. In vitro testing showed a high susceptibility to cephazolin and ciprofloxacin. All patients received ciprofloxacin as first-line therapy. Eighty per cent responded well with complete healing of the ulcer. A second drug was required in 8.5%.
CONCLUSION
Ciprofloxacin therapy can be effective in the treatment of pneumococcal keratitis.

Mesh

Adult
Anti-Infective Agents
Ciprofloxacin
Cornea
Corneal Ulcer
Dacryocystitis
Dacryocystorhinostomy
Eye Infections, Bacterial
Female
Humans
Male
Middle Aged
Pneumococcal Infections
Retrospective Studies
Streptococcus pneumoniae

Language

eng

Pub Type(s)

Journal Article

PubMed ID

12580893